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Patricia Hand
Contact Information

Publications
- Towle, D., Lawson T., Hand, P., Kent, B., and McKernan, M. An intensive short course in molecular biology for undergraduates. Council on Undergraduate Research Quarterly, 79-84, December 2003.
- Horan Hand, P., Slavin-Chiorini, D.C., and Greiner, J.W. Radioimmunotherapy of Cancer Chapter 6: Antibodies and Novel Constructs for Tumor Targeting. In: Abrams, S., Fritzberg, A., (Eds.): Marcel Dekker, Inc., New York, pp. 137-167, 2000.
- Arlen, P., Tsang, K-Y, Marshal, J.L., Chen, A., Steinberg, S.M., Poole, D., Horan Hand, P., Schlom, J., and Hamilton, J.M. The use of a rapid ELISPOT assay to analyze peptide-specific immune responses in carcinoma patients to peptide vs. recombinant poxvirus vaccines. Cancer Immunology and Immunotherapy 49(10): 517-29, 2000.
- Lee, H-S., Shu, L., DePascalis, R., Giuliano, M., Zhu, M., Padlan, E., Horan Hand, P., Schlom, J., Hong, H.J., and Kashmiri, S.V.S. Generation and characterization of a novel single-gene-encoded single-chain immunoglobulin molecule with antigen binding activity and effector functions. Molecular Immunology 1:61-71, 1999.
- McGuinness, R.P., Ge, Y., Patel, S.D., Kashmiri, S.V.S., Horan Hand, P., Schlom, J., Finer, M., and McArthur, J.G. Anti-tumor activity of human T-cells expressing the CC49-zeta chimeric immune receptor. Human Gene Therapy 10(2): 165-173, 1999.
- Santos, A.D., Kashmiri, S.V.S., Horan Hand, P., Schlom, J., and Padlan, E. Generation and characterization of a single-gene encoded single-chain-tetravalent antitumor antibody. Clinical Cancer Research 5; 3118-3123, 1999.
- Buchsbaum, D.J., Khazaeli, M.B., Mayo, M.S., Hand, P.H., Schlom, J., and Meredith, R.F. Evaluation of CH2 deleted HuCC49 for intraperitoneal radiotherapy. Cancer Biotherapy and Radiopharmaceuticals 13(1) 25 Feb. 1998.
- Slavin-Chiorini, D.C., Kashmiri, S.V.S., Lee, Hyun-Sil, Milenic, D.E., Poole, D.J., Bernon, E., Schlom, J., and Horan Hand, P. A CDR-grafted (humanized) domain-deleted antitumor antibody. Cancer Biotherapy and Radiopharmaceuticals 12: 305-316, 1997.
- Abrams, S.I., Horan Hand, P., Tsang, K.Y., and Schlom, J. Mutant ras epitopes as targets for cancer vaccines. Seminars in Oncology 23: 118-134, 1996.
- Kashmiri, S.V.S., Shu, L., Padlan, E.A., Milenic, D.E., Schlom, J., and Horan Hand, P. Generation, characterization and in vivo studies of humanized anticarcinoma antibody CC49. Hybridoma 14: 461-473, 1995.
- Kashmiri, S.V.S., and Horan Hand, P. Genetically engineered anti-tumor monoclonal antibodies. In: Garrett, C. and Sell, S. (Eds.): Cellular Cancer Markers. Humana Press, Totowa, NJ, pp. 393-432, 1995.
- Karr, J.F., Kantor, J.A., Horan Hand, P., Eggensperger, D.L., and Schlom, J. Conservation of the prostate-specific antigen (PSA) gene in primates and the expression of recombinant human PSA in a transfected murine cell line. Cancer Res. 55: 2455-2462, 1995.
- Slavin-Chiorini, D.C., Kashmiri, S.V.S., Schlom, J., Calvo, B., Shu, L.M., Schott, M.E., Milenic, D., Snoy, P., Carrasquillo, J., Anderson, K., and Horan Hand, P. Biologic properties of chimeric CH1 domain-deleted and CH2 domain-deleted anti-carcinoma immunoglobulins. Cancer Res. 55: 5957s-5967s, 1995.
- Shu, L., Chen-F., Q., Horan Hand, P., Schlom, J., and Kashmiri, S.V.S. Generation and characterization of a single-gene encoded single-chain immunoglobulin-interleukin-2 fusion protein. Immunotechnology 1: 231-241, 1995.
Community/University Service
- 2002 to — Community Service — Maine Biomedical Research Coalition
- 2004 to — Community Service — Executive Committee, Maine Marine Research Coalition
- 2006 to — Community Service — Planning Committee, National IDeA Symposium of Biomedical Research Excelence
- 2006 to — Community Service — Reviewer, In-state review of NSF EPSCoR, DOD DEPSCoR proposals
- 2007 to — Community Service — Vice-Chair, Maine Innovation Economy Advisory Board, State of Maine
- 2007 to — Community Service — IDeA Principal Investigator Organizing Committee
- 2008 to — Community Service — Vice-Chair, National EPSCoR/IDeA Foundation Board
- 2008 to — Community Service — Chair, NIH Task Force, National EPSCoR/IDeA Foundation Board
- 2008 to — Community Service — Incorporator, Mount Desert Island Hospital, and Member, Board Quality and Safety Committee
- 2005 to — University Service — Steering Committee, Graduate School of Biomedical Sciences
Grants
- 2004 to 2009 — — Comparative Functional Genomics INBRE in Maine from NCRR/NIH
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